• Adverse pregnancy outcomes among women in Norway with gestational diabetes using three diagnostic criteria 

      Rai, Anam Shakil; Sletner, Line; Jenum, Anne Karen; Øverby, Nina Cecilie; Stafne, Signe Nilssen; Qvigstad, Elisabeth; Pripp, Are Hugo; Sagedal, Linda (Peer reviewed; Journal article, 2023)
      Introduction The aim of this study was to examine the risk of adverse perinatal outcomes in women diagnosed with GDM by the World Health Organization (WHO) 1999 criteria, and in those retrospectively identified by the ...
    • Cohort profile: Epigenetics in Pregnancy (EPIPREG) – Population-based sample of European and South Asian pregnant women with epigenome-wide DNA methylation (850k) in peripheral blood leukocytes 

      Fragoso-Bargas, Nicolas; Opsahl, Julia Onsrud; Kiryushchenko, Nadezhda; Böttcher, Yvonne; Lee-Ødegård, Sindre; Qvigstad, Elisabeth; Richardsen, Kåre Rønn; Waage, Christin; Sletner, Line; Jenum, Anne Karen; Prasad, Rashmi B.; Groop, Leif C.; Moen, Gunn-Helen Øiseth; Birkeland, Kåre Inge; Sommer, Christine (Journal article; Peer reviewed, 2021)
      Pregnancy is a valuable model to study the association between DNA methylation and several cardiometabolic traits, due to its direct potential to influence mother’s and child’s health. Epigenetics in Pregnancy (EPIPREG) ...
    • Effects of race and ethnicity on perinatal outcomes in high-income and upper-middle-income countries: an individual participant data meta-analysis of 2 198 655 pregnancies 

      Sheikh, Jameela; Allotey, John; Kew, Tania; Fernández-Félix, Borja M.; Zamora, Javier; Khalil, Asma; Eskild, Anne; Haavaldsen, Camilla; Magnus, Per Minor; Salvesen, Kjell Å; Skråstad, Ragnhild Bergene; Sletner, Line; Staff, Anne Cathrine; Trogstad, Lill; Thangaratinam, Shakila; Abdollahain, Mali; Adank, Annemarijne; Allen, Rebecca; Andersen, Louise B.; Anggraini, Dewi; Hawkins, Lee Ann; Archer, Lucinda; Askie, Lisa M; Audibert, Francois; Baschat, Ahmet A.; Betran, Ana Pilar; Bhattacharya, Sohinee; Brown, Mark; Browne, Joyce L.; Klipstein-Grobusch, Kerstin; Carbillon, Lionel; Carroli, Guillermo; Cecatti, Jose G; Chappell, Lucy C.; Conde-Agudelo, Agustin; Coomarasamy, Arri; Crovetto, Francesca; da Silva Costa, Fabricio; Daskalakis, George; Dekker, Gustaaf A; Eero, Kajantie; Eisensee, Inge; Facchinetti, Fabio; Farrar, Diane; Ferrazzani, Sergio; Ferrazzi, Enrico; Figueiro-Filho, Ernesto A; Figuera, Francesc; Forest, Jean-Claude; Frusca, Tiziana (Peer reviewed; Journal article, 2022)
      Background Existing evidence on the effects of race and ethnicity on pregnancy outcomes is restricted to individual studies done within specific countries and health systems. We aimed to assess the impact of race and ...
    • Employing fasting plasma glucose to safely limit the use of oral glucose tolerance tests in pregnancy: a pooled analysis of four Norwegian studies 

      Rai, Anam Shakil; Sletner, Line; Jenum, Anne Karen; Øverby, Nina Cecilie; Stafne, Signe Nilssen; Qvigstad, Elisabeth; Pripp, Are Hugo; Sagedal, Linda Reme (Peer reviewed; Journal article, 2023)
      Background/objective: There is no international consensus about the optimal approach to screening and diagnosis of gestational diabetes mellitus (GDM). Fasting plasma glucose (FPG) has been proposed as an alternative ...
    • Epigenome-wide association study of serum folate in maternal peripheral blood leukocytes 

      Fragoso-Bargas, Nicolas; Page, Christian Magnus; Joubert, Bonnie R.; London, Stephanie J.; Lee-Ødegård, Sindre; Opsahl, Julia Onsrud; Sletner, Line; Jenum, Anne Karen; Qvigstad, Elisabeth; Prasad, Rashmi B.; Moen, Gunn-Helen Øiseth; Birkeland, Kåre Inge; Sommer, Christine (Peer reviewed; Journal article, 2023)
      Aim: To perform an epigenome-wide association study (EWAS) of serum folate in maternal blood. Methods: Cross-ancestry (Europeans = 302, South Asians = 161) and ancestry-specific EWAS in the EPIPREG cohort were performed, ...
    • Identifying women with gestational diabetes based on maternal characteristics: an analysis of four Norwegian prospective studies 

      Rai, Anam Shakil; Sletner, Line; Jenum, Anne Karen; Øverby, Nina Cecilie; Stafne, Signe Nilssen; Lekva, Tove; Pripp, Are Hugo; Sagedal, Linda Reme (Journal article; Peer reviewed, 2021)
      Background There is still no worldwide agreement on the best diagnostic thresholds to define gestational diabetes (GDM) or the optimal approach for identifying women with GDM. Should all pregnant women perform an oral ...
    • Insulin and Body Mass Index Decrease Serum Soluble Leptin Receptor Levels in Humans 

      Sommer, Christine; Vangberg, Kjersti G.; Moen, Gunn-Helen Øiseth; Evans, David M.; Lee-Ødegård, Sindre; Høgestøl, Ingvild Kristine; Sletner, Line; Jenum, Anne Karen; Drevon, Christian A.; Gulseth, Hanne Løvdal; Birkeland, Kåre Inge (Peer reviewed; Journal article, 2022)
      Context Serum soluble leptin receptor (sOb-R) may protect against future type 2 diabetes or serve as a marker for protective features, but how sOb-R is regulated is largely unknown. Objective This work aimed to test ...
    • Seasonal variation in gestational diabetes mellitus among women in Norway: a national population-based study 

      Stalheim, Astrid Melteig; Iversen, Marjolein M.; Jenum, Anne Karen; Sletner, Line; Stafne, Signe Nilssen; Qvigstad, Elisabeth; Sagedal, Linda Reme; Nilsen, Roy Miodini; Aasheim, Vigdis; Strandberg, Ragnhild Bjarkøy (Peer reviewed; Journal article, 2023)
      Objectives Previous research on seasonal variation in the incidence of gestational diabetes mellitus (GDM) has shown inconclusive results. Furthermore, little is known about whether a seasonal variation in GDM might be ...